The hormonal therapy is then used when the cancer already was spread of the prostate. Also it can be managed for some men who are under x-ray or had made surgery, to prevent the return of its cancer. The hormonal therapy for the prostate cancer acts in the metabolic ways that the body uses to produce the DHT. A feedback cycle involving testicules, hipotlamo, hipfise, supply-renais and prostate controls the sanguineous levels of DHT. First, the low sanguineous levels of DHT stimulate hipotlamo to produce gonadotrofina hormone liberating (GnRH). The GnRH then stimulates hipfise to produce hormone luteinizante (LH), which stimulates the testicules to produce testosterone. Finally, the testosterone of the testicules and dehidroepiandrosterona of the glands supply-renais stimulate the prostate to produce more DHT. The hormonal therapy diminishes the DHT levels therefore interrupts this saw metabolic in some point.
Diverse forms of hormonal therapy for the prostate cancer exist: it is the surgery to remove the testicules. As the testicules produce most of the testosterone of the body, its surgical removal makes with that the testosterone levels fall immediately afterwards. With this, the prostate not only leaves to receive stimulaton from the testosterone to produce more DHT, as well as it does not possess testosterone enough to transform it into DHT.Orquiectomia? Antiandrgenos flutamida, bicalutamida, nilutamida, and acetate of ciproterona are medicines as that directly they block the actions of the testosterone and the DHT in the interior of the cells of the prostate cancer. Medicines that block the production of the andrgenos supply-renais as the DHEA includes cetoconazol and the aminoglutetimida one. As the glands supply-renais only produce about 5% of the andrgenos of the body, these medicines are generally used only in combination with other methods that can block 95% of andrgenos produced for the testicules. These agreed methods are called total andrognico blockade (BAT). The BAT also can be gotten with the use of antiandrgenos.